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KMID : 0376619930180030152
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Seoul Journal of Psychiatry
1993 Volume.18 No. 3 p.152 ~ p.158
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Effects of Neuroleptic Treatments on Serum β-Endorphin Level in Newly Admitted Male schizophrenics
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김철응
하규섭/강대엽/김용식
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Abstract
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The effects of neuroleptic treatments on serum β-endorphin level were examined in 11 newly admitted male schizophrenics who did not take medications for at least 6 months Serumβ-endorphin levels were assayed before and after neuroleptic
treatment
at
day 1, 7, 28. Serum β-endorphin mean basal levels of schizophrenics did not differ from age-matched normal control subjects. But after treatment, the mean levels of β-endorphin were significantly elevated at 7 & at day 28 There was no
significant
correlati8on between serum β-endorphin levels & BPRS total score. But at day 28, there was significant correlation between serum β-endorphin levels and anxiety-depression subscore of BPRS.
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KEYWORD
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